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Purification and characterization of macrolide 2'-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin.

Macrolide 2'-phosphotransferase [MPH(2')] was purified 90-fold from an erythromycin-resistant strain of Escherichia coli, and its enzymatic properties were investigated. MPH(2') is an inducible intracellular enzyme which showed high levels of activity with 14-member-ring macrolides and extremely low...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: O'Hara, K, Kanda, T, Ohmiya, K, Ebisu, T, Kono, M
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2478074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1354
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