Purification and characterization of macrolide 2'-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin.

Macrolide 2'-phosphotransferase [MPH(2')] was purified 90-fold from an erythromycin-resistant strain of Escherichia coli, and its enzymatic properties were investigated. MPH(2') is an inducible intracellular enzyme which showed high levels of activity with 14-member-ring macrolides and extremely low...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	O'Hara, K, Kanda, T, Ohmiya, K, Ebisu, T, Kono, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2478074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1354
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