Activity of ICI 195,739, a new oral triazole, compared with that of ketoconazole in the therapy of experimental murine blastomycosis.

ICI 195,739, a novel orally active triazole, proved 50 times as potent as ketoconazole, produced a clinical cure, and completely eradicated residual infection in a murine model of pulmonary blastomycosis. No other previously tested azole has shown similar activity. Fungicidal activity against Blasto...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Tucker, R M, Hanson, L H, Brummer, E, Stevens, D A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2729949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.4.573
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