Molecular cloning and genetic analysis of a chloramphenicol acetyltransferase determinant from Clostridium difficile.

A gene bank from a clinical isolate of Clostridium difficile expressing high chloramphenicol acetyltransferase activity was constructed by cloning Sau3A-cleaved clostridial DNA fragments into the plasmid vector pUC13. Among 1,020 clones tested, 11 were resistant to chloramphenicol; 1 of these, with...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Wren, B W, Mullany, P, Clayton, C, Tabaqchali, S
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1988
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172379/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2847649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.8.1213
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