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Molecular cloning and genetic analysis of a chloramphenicol acetyltransferase determinant from Clostridium difficile.

A gene bank from a clinical isolate of Clostridium difficile expressing high chloramphenicol acetyltransferase activity was constructed by cloning Sau3A-cleaved clostridial DNA fragments into the plasmid vector pUC13. Among 1,020 clones tested, 11 were resistant to chloramphenicol; 1 of these, with...

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Detalhes bibliográficos
Main Authors: Wren, B W, Mullany, P, Clayton, C, Tabaqchali, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC172379/
https://ncbi.nlm.nih.gov/pubmed/2847649
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