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Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12.

Quinolone antimicrobial agents are known to interact with DNA gyrase, but the mechanism by which bacterial cell death occurs is not fully understood. In order to determine whether there is a correlation between quinolone-induced inhibition of early (i.e., 10 to 15 min) DNA synthesis and potency (MIC...

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Збережено в:
Бібліографічні деталі
Опубліковано в::Antimicrob Agents Chemother
Автори: Chow, R T, Dougherty, T J, Fraimow, H S, Bellin, E Y, Miller, M H
Формат: Artigo
Мова:Inglês
Опубліковано: American Society for Microbiology (ASM) 1988
Предмети:
Онлайн доступ:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3056251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.8.1113
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