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Antibacterial properties of (2,3)-alpha- and (2,3)-beta-methylene analogs of penicillin G.

The penam nucleus can assume two conformations; these are designated open and closed. The synthetic (2,3)-alpha- and (2,3)-beta-methylenepenams can be regarded as analogs of the open and closed conformations, respectively. It has been shown that the beta-methylenepenams are essentially inactive, sug...

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Detalles Bibliográficos
Main Authors: Christenson, J G, Pruess, D L, Talbot, M K, Keith, D D
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC172334/
https://ncbi.nlm.nih.gov/pubmed/3190190
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