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Antibacterial properties of (2,3)-alpha- and (2,3)-beta-methylene analogs of penicillin G.

The penam nucleus can assume two conformations; these are designated open and closed. The synthetic (2,3)-alpha- and (2,3)-beta-methylenepenams can be regarded as analogs of the open and closed conformations, respectively. It has been shown that the beta-methylenepenams are essentially inactive, sug...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Christenson, J G, Pruess, D L, Talbot, M K, Keith, D D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3190190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.7.1005
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