Concentrations of flucloxacillin in heart valves and subcutaneous and muscle tissues of patients undergoing open-heart surgery.

Thirty-seven patients were given a single, 2-g intravenous bolus injection of flucloxacillin prior to open-heart surgery. Within 12 h, flucloxacillin concentrations in serum and heart valves declined from 125.2 to 4.4 micrograms/ml and from 16.5 to 3.7 micrograms/g, respectively. Concentrations in s...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Frank, U, Schmidt-Eisenlohr, E, Schlosser, V, Spillner, G, Schindler, M, Daschner, F D
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1988
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3415213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.6.930
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