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Concentrations of flucloxacillin in heart valves and subcutaneous and muscle tissues of patients undergoing open-heart surgery.

Thirty-seven patients were given a single, 2-g intravenous bolus injection of flucloxacillin prior to open-heart surgery. Within 12 h, flucloxacillin concentrations in serum and heart valves declined from 125.2 to 4.4 micrograms/ml and from 16.5 to 3.7 micrograms/g, respectively. Concentrations in s...

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Detalhes bibliográficos
Main Authors: Frank, U, Schmidt-Eisenlohr, E, Schlosser, V, Spillner, G, Schindler, M, Daschner, F D
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC172310/
https://ncbi.nlm.nih.gov/pubmed/3415213
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