Selective CXCR4 antagonism by Tat: Implications for in vivo expansion of coreceptor use by HIV-1
Chemokines and chemokine receptors play important roles in HIV-1 infection and tropism. CCR5 is the major macrophage-tropic coreceptor for HIV-1 whereas CXC chemokine receptor 4 (CXCR4) serves the counterpart function for T cell-tropic viruses. An outstanding biological mystery is why only R5-HIV-1...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11466 |
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