Pharmacokinetics of fluconazole in cerebrospinal fluid and serum in human coccidioidal meningitis.
The pharmacokinetics of fluconazole, a new oral azole, were evaluated in cerebrospinal fluid and sera of eight patients with coccidioidal meningitis. At a dose of 50 mg/day, peak concentrations of 2.5 to 3.5 and 2.0 to 2.3 micrograms/ml occurred at 2 to 6 and 4 to 8 h in serum and cerebrospinal flui...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1988
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2835002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.3.369 |
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