Bioavailability of oral trimetrexate in patients with acquired immunodeficiency syndrome.

The combination of the lipophilic antifolate trimetrexate and the rescue agent leucovorin has shown promise in the treatment of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. The pharmacokinetic behavior of trimetrexate administered either by intravenous bolus or...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Rogers, P, Allegra, C J, Murphy, R F, Drake, J C, Masur, H, Poplack, D G, Chabner, B A, Parrillo, J E, Lane, H C, Balis, F M
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1988
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2966610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.3.324
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