Development of beta-lactam resistance and increased quinolone MICs during therapy of experimental Pseudomonas aeruginosa endocarditis.

The in vivo efficacies of pefloxacin, a new fluoroquinolone, and amikacin-ceftazidime were compared in 50 rabbits with experimental aortic endocarditis caused by Pseudomonas aeruginosa. Animals were randomly chosen to receive 4 or 10 days of no therapy (controls), pefloxacin (40 mg/kg [body weight]...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Bayer, A S, Hirano, L, Yih, J
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1988
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3129985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.2.231
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