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Bactericidal interactions of a beta-lactam and beta-lactamase inhibitors in experimental Pseudomonas aeruginosa endocarditis caused by a constitutive overproducer of type Id beta-lactamase.

We investigated the in vitro and in vivo effects of a combination of a beta-lactam (ceftazidime) and a beta-lactamase inhibitor (dicloxacillin) to synergistically kill a ceftazidime-resistant variant, Pseudomonas aeruginosa PA-48, which overproduces type Id cephalosporinase constitutively. In vitro,...

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Bibliografische gegevens
Hoofdauteurs: Bayer, A S, Selecky, M, Babel, K, Hirano, L, Yih, J, Parr, T R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1987
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC175033/
https://ncbi.nlm.nih.gov/pubmed/3124738
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