Inhibition of Amphotericin B (Fungizone) Toxicity to Cells by Egg Lecithin-Glycocholic Acid Mixed Micelles

Mixed micelles prepared from egg lecithin and the sodium salt of glycocholic acid markedly inhibited amphotericin B toxicity to mammalian cells without significantly affecting the antifungal effects of the drug.

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Bibliographic Details
Main Authors: Brajtburg, Janina, Elberg, Svetlana, Kobayashi, George S., Medoff, Gerald
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC172071/
https://ncbi.nlm.nih.gov/pubmed/2088196
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