Isoniazid pharmacokinetics in children treated for respiratory tuberculosis

Aims: To define the pharmacokinetics of isoniazid (INH) in children with tuberculosis in relation to the N-acetyltransferase 2 (NAT2) genotype. Methods: The first order elimination rate constant (k) and area under the concentration curve (AUC) were calculated in 64 children <13 years of age (medi...

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Detalhes bibliográficos
Main Authors: Schaaf, H, Parkin, D, Seifart, H, Werely, C, Hesseling, P, van Helden, P D, Maritz, J, Donald, P
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1720436/
https://ncbi.nlm.nih.gov/pubmed/15908628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/adc.2004.052175
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