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Pharmacokinetics of Isoniazid, Rifampin, and Pyrazinamide in Children Younger than Two Years of Age with Tuberculosis: Evidence for Implementation of Revised World Health Organization Recommendations

The World Health Organization (WHO) recently issued revised first-line antituberculosis (anti-TB) drug dosage recommendations for children. No pharmacokinetic studies for these revised dosages are available for children <2 years. The aim of the study was to document the pharmacokinetics of the fi...

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Detalhes bibliográficos
Main Authors: Thee, S., Seddon, J. A., Donald, P. R., Seifart, H. I., Werely, C. J., Hesseling, A. C., Rosenkranz, B., Roll, S., Magdorf, K., Schaaf, H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232790/
https://ncbi.nlm.nih.gov/pubmed/21968358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05429-11
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