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Illimaquinone, a selective inhibitor of the RNase H activity of human immunodeficiency virus type 1 reverse transcriptase.

We studied the effect of the natural marine substance illimaquinone on the catalytic activities of reverse transcriptase from human immunodeficiency virus type 1. Illimaquinone inhibited the RNase H activity of the enzyme at concentrations of 5 to 10 microgram/ml, whereas RNA-dependent DNA polymeras...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Loya, S, Tal, R, Kashman, Y, Hizi, A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.10.2009
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