Illimaquinone, a selective inhibitor of the RNase H activity of human immunodeficiency virus type 1 reverse transcriptase.

We studied the effect of the natural marine substance illimaquinone on the catalytic activities of reverse transcriptase from human immunodeficiency virus type 1. Illimaquinone inhibited the RNase H activity of the enzyme at concentrations of 5 to 10 microgram/ml, whereas RNA-dependent DNA polymeras...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Loya, S, Tal, R, Kashman, Y, Hizi, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171980/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705412/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.10.2009
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