Differential role of transcription-coupled repair in UVB-induced G(2) arrest and apoptosis in mouse epidermis

Nucleotide excision repair (NER), apoptosis, and cell-cycle regulation are major defense mechanisms against the carcinogenic effects of UVB light. NER eliminates UVB-induced DNA photolesions via two subpathways: global genome repair (GGR) and transcription-coupled repair (TCR). Defects in NER result...

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Detalhes bibliográficos
Main Authors: van Oosten, Marijke, Rebel, Heggert, Friedberg, Errol C., van Steeg, Harry, van der Horst, Gijsbertus T. J., van Kranen, Henk J., Westerman, Anja, van Zeeland, Albert A., Mullenders, Leon H. F., de Gruijl, Frank R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17189/
https://ncbi.nlm.nih.gov/pubmed/11005836
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