Nalaganje...
Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study
The intracellular activity of the p53 tumor suppressor protein is regulated through a feedback loop involving its transcriptional target, mdm2. We present a simple mathematical model suggesting that, under certain circumstances, oscillations in p53 and Mdm2 protein levels can emerge in response to a...
Shranjeno v:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2000
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17186/ https://ncbi.nlm.nih.gov/pubmed/11016968 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|