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6-(3,4-Dichlorophenoxy)-3-(ethylthio)-2-pyridincarbonitrile inhibits poliovirus uncoating.

We investigated the mode of action of 6-(3,4-dichlorophenoxy-3-(ethylthio)-2-pyridincarbonitrile against poliovirus. This agent effectively blocked the synthesis of poliovirus proteins and RNA when it was added at the beginning of infection. Poliovirus attachment and internalization into HeLa cells...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: González, M E, Almela, M J, Yacout, M, Carrasco, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171796/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168147/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1259
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