In vitro and in vivo activities of WIN 54954, a new broad-spectrum antipicornavirus drug.

WIN 54954 (5-[5-[2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy]pentyl]-3- methylisoxazole) is a new member of the class of broad-spectrum antipicornavirus compounds known to bind in a hydrophobic pocket within virion capsid protein VP1. In plaque reduction assays, WIN 54954 reduced plaque formation...

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Библиографические подробности
Главные авторы: Woods, M G, Diana, G D, Rogge, M C, Otto, M J, Dutko, F J, McKinlay, M A
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC172823/
https://ncbi.nlm.nih.gov/pubmed/2559655
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