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High-affinity ouabain binding by a chimeric gastric H(+),K(+)-ATPase containing transmembrane hairpins M3-M4 and M5-M6 of the α(1)-subunit of rat Na(+),K(+)-ATPase
Na(+),K(+)-ATPase and gastric H(+),K(+)-ATPase are two related enzymes that are responsible for active cation transport. Na(+),K(+)-ATPase activity is inhibited specifically by ouabain, whereas H(+),K(+)-ATPase is insensitive to this drug. Because it is not known which parts of the catalytic subunit...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17179/ https://ncbi.nlm.nih.gov/pubmed/11016952 |
| タグ: |
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