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Sucralfate significantly reduces ciprofloxacin concentrations in serum.

The effect of sucralfate on the bioavailability of ciprofloxacin was evaluated in eight healthy subjects utilizing a randomized, crossover design. The area under the concentration-time curve from 0 to 12 h was reduced from 8.8 to 1.1 micrograms.h/ml by sucralfate (P less than 0.005). Similarly, the...

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Detalles Bibliográficos
Main Authors: Garrelts, J C, Godley, P J, Peterie, J D, Gerlach, E H, Yakshe, C C
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC171725/
https://ncbi.nlm.nih.gov/pubmed/2360833
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