Sucralfate significantly reduces ciprofloxacin concentrations in serum.

The effect of sucralfate on the bioavailability of ciprofloxacin was evaluated in eight healthy subjects utilizing a randomized, crossover design. The area under the concentration-time curve from 0 to 12 h was reduced from 8.8 to 1.1 micrograms.h/ml by sucralfate (P less than 0.005). Similarly, the...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Garrelts, J C, Godley, P J, Peterie, J D, Gerlach, E H, Yakshe, C C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2360833/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.5.931
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