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An HIV Feedback Resistor: Auto-Regulatory Circuit Deactivator and Noise Buffer

Animal viruses (e.g., lentiviruses and herpesviruses) use transcriptional positive feedback (i.e., transactivation) to regulate their gene expression. But positive-feedback circuits are inherently unstable when turned off, which presents a particular dilemma for latent viruses that lack transcriptio...

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Autors principals: Weinberger, Leor S, Shenk, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1717016/
https://ncbi.nlm.nih.gov/pubmed/17194214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050009
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