Azole susceptibility and hyphal formation in a cytochrome P-450-deficient mutant of Candida albicans.

A cytochrome P-450-deficient mutant of Candida albicans, strain D10, was employed to study the mode of action of imidazole antifungal agents. This mutant accumulates exclusively 14-alpha-methylsterols, resulting in a sterol profile which mimics that of azole-treated wild-type strains. Since the wide...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lees, N D, Broughton, M C, Sanglard, D, Bard, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2193620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.5.831
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