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Inhibition of herpes simplex virus type 2 growth by phosphorothioate oligodeoxynucleotides.

Phosphorothioate homo-oligodeoxynucleotides were found to be potent inhibitors of herpes simplex virus type 2 (HSV-2) but less potent for HSV-1 in cell culture studies. Oligomers with longer chain lengths were more active against HSV-2 than those with shorter ones. Of all the compounds examined, the...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Gao, W Y, Hanes, R N, Vazquez-Padua, M A, Stein, C A, Cohen, J S, Cheng, Y C
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2163243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.5.808
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