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In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes.

Some quinolone antibiotics cause increases in levels of theophylline in plasma that lead to serious adverse effects. We investigated the mechanism of this interaction by developing an in vitro system of human liver microsomes. Theophylline (1,3-dimethylxanthine) was incubated with human liver micros...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Sarkar, M, Polk, R E, Guzelian, P S, Hunt, C, Karnes, H T
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2344166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.4.594
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