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Ly-6C(hi) monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

Macrophage accumulation participates decisively in the development and exacerbation of atherosclerosis. Circulating monocytes, the precursors of macrophages, display heterogeneity in mice and humans, but their relative contribution to atherogenesis remains unknown. We report here that the Ly-6C(hi)...

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Autors principals: Swirski, Filip K., Libby, Peter, Aikawa, Elena, Alcaide, Pilar, Luscinskas, F. William, Weissleder, Ralph, Pittet, Mikael J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716211/
https://ncbi.nlm.nih.gov/pubmed/17200719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29950
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