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Ly-6C(hi) monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

Macrophage accumulation participates decisively in the development and exacerbation of atherosclerosis. Circulating monocytes, the precursors of macrophages, display heterogeneity in mice and humans, but their relative contribution to atherogenesis remains unknown. We report here that the Ly-6C(hi)...

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Detalles Bibliográficos
Main Authors: Swirski, Filip K., Libby, Peter, Aikawa, Elena, Alcaide, Pilar, Luscinskas, F. William, Weissleder, Ralph, Pittet, Mikael J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716211/
https://ncbi.nlm.nih.gov/pubmed/17200719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29950
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