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Lack of association between COMT gene and deficit/nondeficit schizophrenia
BACKGROUND: The dopamine dysregulation hypothesis of schizophrenia posits that positive, negative and cognitive symptoms correlate with cortical/subcortical imbalances in dopaminergic transmission. A functional polymorphism (Val(158)Met) in the catechol-O-methyltransferase (COMT) gene is implicated...
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Main Authors: | , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2006
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1716164/ https://ncbi.nlm.nih.gov/pubmed/17173666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-9081-2-42 |
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