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Identification of mutations in the duplicated region of the polycystic kidney disease 1 gene (PKD1) by a novel approach.

Mutation screening of the major autosomal dominant polycystic kidney disease gene (PKD1) has been complicated by the large transcript size (> 14 kb) and by reiteration of the genomic area encoding 75% of the protein on the same chromosome (the HG loci). The sequence similarity between the PKD1 an...

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Bibliografiska uppgifter
Huvudupphovsmän: Peral, B, Gamble, V, Strong, C, Ong, A C, Sloane-Stanley, J, Zerres, K, Winearls, C G, Harris, P C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716112/
https://ncbi.nlm.nih.gov/pubmed/9199561
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