HIV Protease Inhibitors Decrease VEGF/HIF-1α Expression and Angiogenesis in Glioblastoma Cells

Glioblastomas are malignant brain tumors that are rarely curable, even with aggressive therapy (surgery, chemotherapy, and radiation). Glioblastomas frequently display loss of PTEN and/or epidermal growth factor receptor activation, both of which activate the PI3K pathway. This pathway can increase...

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Main Authors: Pore, Nabendu, Gupta, Anjali K, Cerniglia, George J, Mait, Amit
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2006
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Brief Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716015/
https://ncbi.nlm.nih.gov/pubmed/17132220
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