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Deletion of RB exons 24 and 25 causes low-penetrance retinoblastoma.

A deletion in the tumor-suppressor gene, RB, discovered by quantitative multiplex PCR, shows low penetrance (LP), since only 39% of eyes at risk in this family develop retinoblastoma. The 4-kb deletion spanning exons 24 and 25 (delta24-25) is the largest ever observed in an LP retinoblastoma family....

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Sonraí Bibleagrafaíochta
Main Authors: Bremner, R, Du, D C, Connolly-Wilson, M J, Bridge, P, Ahmad, K F, Mostachfi, H, Rushlow, D, Dunn, J M, Gallie, B L
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715941/
https://ncbi.nlm.nih.gov/pubmed/9326321
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