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Association mapping of disease loci, by use of a pooled DNA genomic screen.

Genomic screening to map disease loci by association requires automation, pooling of DNA samples, and 3,000-6,000 highly polymorphic, evenly spaced microsatellite markers. Case-control samples can be used in an initial screen, followed by family-based data to confirm marker associations. Association...

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Detalhes bibliográficos
Main Authors: Barcellos, L F, Klitz, W, Field, L L, Tobias, R, Bowcock, A M, Wilson, R, Nelson, M P, Nagatomi, J, Thomson, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715937/
https://ncbi.nlm.nih.gov/pubmed/9326338
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