TMPRSS2-ERG Gene Fusion Causing ERG Overexpression Precedes Chromosome Copy Number Changes in Prostate Carcinomas and Paired HGPIN Lesions

TMPRSS2-ETS gene fusions have been found recurrently in prostate carcinomas, but not in the presumed precursor lesion, high-grade prostatic intraepithelial neoplasia (HGPIN). However, HGPIN lesions may share chromosomal changes with prostate cancer. To determine the relative order of genetic events...

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Main Authors: Cerveira, Nuno, Ribeiro, Franclim R, Peixoto, Ana, Costa, Vera, Henrique, Rui, Jerónimo, Carmen, Teixeira, Manuel R
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715930/
https://ncbi.nlm.nih.gov/pubmed/17032499
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