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Overexpression of PIAS3 Suppresses Cell Growth and Restores the Drug Sensitivity of Human Lung Cancer Cells in Association with PI3-K/Akt Inactivation

Constitutively activated signal transducers and activators of transcription (STAT) are reported to cause uncontrolled transmission of growth signals. In this study, we analyzed the roles of an inhibitor of STAT, protein inhibitor of activated STAT (PIAS) 3, in the development of lung cancer. Treatme...

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Detalhes bibliográficos
Main Authors: Ogata, Yoshitaka, Osaki, Tadashi, Naka, Tetsuji, Iwahori, Kota, Furukawa, Mitsugi, Nagatomo, Izumi, Kijima, Takashi, Kumagai, Toru, Yoshida, Mitsuhiro, Tachibana, Isao, Kawase, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715929/
https://ncbi.nlm.nih.gov/pubmed/17032498
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