Carregant...

Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.

Hereditary nonpolyposis colorectal cancer (HNPCC) is a common autosomal dominant cancer-susceptibility condition characterized by early onset colorectal cancer. Germ-line mutations in one of four DNA mismatch repair (MMR) genes, hMSH2, hMLH1, hPMS1, or hPMS2, are known to cause HNPCC. Although many...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wijnen, J, Khan, P M, Vasen, H, van der Klift, H, Mulder, A, van Leeuwen-Cornelisse, I, Bakker, B, Losekoot, M, Møller, P, Fodde, R
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715907/
https://ncbi.nlm.nih.gov/pubmed/9311737
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!