Uptake and intracellular activity of an optically active ofloxacin isomer in human neutrophils and tissue culture cells.

The penetration of an optically active ofloxacin isomer [(-)-ofloxacin] into human neutrophils and different tissue culture cells (HEp-2, McCoy, MDCK, and Vero) was studied and compared with that of ofloxacin by a fluorometric assay. The cellular-to-extracellular-concentration ratios (C/E) of (-)-of...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Pascual, A, Garcia, I, Perea, E J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171573/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2327777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.2.277
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