Uptake and Intracellular Activity of Linezolid in Human Phagocytes and Nonphagocytic Cells

The intracellular penetration and activity of linezolid in human polymorphonuclear leukocytes and tissue-cultured cells (McCoy) were evaluated. Linezolid reached intracellular concentrations slightly greater than extracellular ones in both types of cell. The uptake was rapid and not saturable and wa...

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Bibliographic Details
Main Authors: Pascual, Álvaro, Ballesta, Sofía, García, Isabel, Perea, Evelio J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC132792/
https://ncbi.nlm.nih.gov/pubmed/12435714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.4013-4015.2002
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