Uptake and Intracellular Activity of Linezolid in Human Phagocytes and Nonphagocytic Cells

The intracellular penetration and activity of linezolid in human polymorphonuclear leukocytes and tissue-cultured cells (McCoy) were evaluated. Linezolid reached intracellular concentrations slightly greater than extracellular ones in both types of cell. The uptake was rapid and not saturable and wa...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Pascual, Álvaro, Ballesta, Sofía, García, Isabel, Perea, Evelio J.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Pharmacology
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.4013-4015.2002
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