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Efficacy of a hydroxynaphthoquinone, 566C80, in experimental Pneumocystis carinii pneumonitis.

The efficacy of a new class of drugs for Pneumocystis carinii pneumonitis was demonstrated. 566C80, a hydroxynaphthoquinone, administered orally in a dose of greater than or equal to 100 mg/kg of body weight per day prophylactically prevented P. carinii pneumonitis in 90% or more of rats, while all...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Principais autores: Hughes, W T, Gray, V L, Gutteridge, W E, Latter, V S, Pudney, M
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1990
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2327770/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.2.225
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