Efficacy of a hydroxynaphthoquinone, 566C80, in experimental Pneumocystis carinii pneumonitis.

The efficacy of a new class of drugs for Pneumocystis carinii pneumonitis was demonstrated. 566C80, a hydroxynaphthoquinone, administered orally in a dose of greater than or equal to 100 mg/kg of body weight per day prophylactically prevented P. carinii pneumonitis in 90% or more of rats, while all...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Hughes, W T, Gray, V L, Gutteridge, W E, Latter, V S, Pudney, M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171561/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2327770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.2.225
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