Restriction analysis of the structural α-L-fucosidase gene and its linkage to fucosidosis

Human α-L-fucosidase is a lysosomal enzyme responsible for hydrolysis of α-L-fucoside linkages in fucoglycoconjugates. A single gene, FUCA 1, located on chromosome 1p34.1–1p36.1 encodes for α-L-fucosidase activity. To gain insight into the nature of the molecular defects leading to fucosidosis, we h...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Darby, John K., Willems, Patrick J., Nakashima, Phil, Johnsen, Jeff, Ferrell, Robert E., Wijsman, Ellen M., Gerhard, Daniella S., Dracopoli, Nicholas C., Housman, David, Henke, Jurgen, Fowler, Michael L., Shows, Thomas B., O'Brien, John S., Cavalli-Sforza, Luca L.
Formato: Artigo
Idioma:Inglês
Publicado: 1988
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715555/
https://ncbi.nlm.nih.gov/pubmed/2903667
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares