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Molecular analysis of male-viable deletions and duplications allows ordering of 52 DNA probes on proximal Xq.

While performing a systematic search for chromosomal microdeletions in patients with clinically complex X-linked syndromes, we have observed that large male-viable deletions and duplications are clustered in heterochromatic regions of the X chromosome. Apart from the Xp21 band, where numerous deleti...

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Detalhes bibliográficos
Main Authors: Cremers, F P, van de Pol, T J, Wieringa, B, Hofker, M H, Pearson, P L, Pfeiffer, R A, Mikkelsen, M, Tabor, A, Ropers, H H
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715498/
https://ncbi.nlm.nih.gov/pubmed/3177387
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