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On the possibility of pleiotropic monogenic control of hereditary polyposis and primary cancer of the colon.

The results of the segregation analysis of hereditary adenomatous polyposis and primary cancer of the colon are given, taking into account the age-dependent manifestation of genotypes and the specificity of pedigree sampling. The results are used for testing the hypothesis of pleiotropic monogenic c...

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Autors principals: Ginsburg, E K, Axenovich, T I, Altshouler, B A, Bazhenova, M D
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715412/
https://ncbi.nlm.nih.gov/pubmed/2536218
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