Loss of heterozygosity in a gene coding for a thyroid hormone receptor in lung cancers

The ERBAβ gene codes for a DNA-binding thyroid hormone receptor (THR) and maps to chromosome 3p21-p25, overlapping a 3p deletion characterizing small-cell lung carcinoma (SCLC). A DNA clone detecting an RFLP at the ERBAβ locus has been used to probe a large number of lung .tumors. Virtually all SCLC...

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Detalhes bibliográficos
Main Authors: Leduc, François, Brauch, Hiltrud, Hajj, Camile, Dobrovic, Alexander, Kaye, Frederick, Gazdar, Adi, Harbour, J. William, Pettengill, Olive S., Sorenson, George D., van den Berg, A., Kok, K., Campling, Barbara, Paquin, François, Bradley, W. E. C., Zbar, Berton, Minna, John, Buys, Charles, Ayoub, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715394/
https://ncbi.nlm.nih.gov/pubmed/2536219
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