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A test of the heterozygote-advantage hypothesis in cystic fibrosis carriers.

We report a test of the hypothesis that the high frequency of cystic fibrosis (CF) in Caucasian populations is due to a fertility advantage in CF carriers. One hundred forty-three grandparent couples of Utah CF cases were compared with 20 replicate sets of matched control couples drawn from the Utah...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jorde, L B, Lathrop, G M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 1988
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715197/
https://ncbi.nlm.nih.gov/pubmed/3369446
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